Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology

Adipocyte turnover and adipose morphology ADIPOCYTE TURNOVER: RELEVANCE TO HUMAN ADIPOSE TISSUE MORPHOLOGY Running head: Adipocyte turnover and adipose morphology

Department of Medicine, Karolinska Institutet at Karolinska University Hospital, 141 86, Stockholm, Sweden, Institute for Theoretical Biology (ITB), Humboldt University Berlin and Charité, Invalidenstrasse 43, 10115 Berlin, Germany, Department of Cell and Molecular Biology, Karolinska Institutet, 171 77 Stockholm, Sweden, Department of Mathematics, Stockholm University, 106 91 Stockholm, Sweden...

Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology

OBJECTIVE Adipose tissue may contain few large adipocytes (hypertrophy) or many small adipocytes (hyperplasia). We investigated factors of putative importance for adipose tissue morphology. RESEARCH DESIGN AND METHODS Subcutaneous adipocyte size and total fat mass were compared in 764 subjects with BMI 18-60 kg/m(2). A morphology value was defined as the difference between the measured adipoc...

Review Paper: Adipose Tissue, Adipocyte Differentiation, and Variety of Stem Cells in Tissue Engineering and Regeneration

Human adipose tissue represents an abundant, practical and appealing source of donor tissue for autologous cell replacement. Recent findings have shown that stem cells within the stromalvascular fraction of adipose tissue display a multilineage developmental potential. Adipose tissue-derived stem cells can be differentiated towards adipogenic, osteogenic, chondrogenic,myogenic and neurogenic li...

CIDE Family-Mediated Unique Lipid Droplet Morphology in White Adipose Tissue and Brown Adipose Tissue Determines the Adipocyte Energy Metabolism

White adipose tissue (WAT) stores energy as triacylglycerol in preparation for fasting state. In contrast, brown adipose tissue (BAT) consumes energy and produces heat in a cold environment. One of the major differences between these two adipose tissues is the morphology of the intracellular lipid droplet (LD), which is large and unilocular in WAT and small and multilocular in BAT. Although the...

Adipocyte, adipose tissue, and infectious disease.